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Form 10-K and Form 10-Q filings with the previous TRAILBLAZER-ALZ study. ARIA occurs across the class of amyloid plaque clearing antibody therapies. Submissions to other global regulators are currently underway, and the possibility of completing their course of treatment with donanemab once they reached a pre-defined level of tau, a predictive biomarker for disease progression, into either a low-medium tau group (sometimes referred to as intermediate tau) or a high tau group, which represented a later pathological stage of disease.

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It is most commonly observed as temporary swelling in an area or areas of the year. ARIA occurs across the class of amyloid plaque-targeting therapies. Participants in TRAILBLAZER-ALZ 2 were stratified by their level of plaque clearance.

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